Bio-Inspired Traffic Pattern Generation for Multi-AMR Systems

In intralogistics, autonomous mobile robots (AMRs) operate without predefined paths, leading to complex traffic patterns and potential conflicts that impact system efficiency.This paper proposes a bio-inspired optimization method for autonomously generating spatial movement constraints for autonomous mobile robots (AMRs).Unlike traditional multi-ag

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Re-Use of Established Drugs for Anti-Metastatic Indications

Most patients that die from cancer do not die caroline gardner cards sale due to the primary tumor but due to the development of metastases.However, there is currently still no drug on the market that specifically addresses and inhibits metastasis formation.This lack was, in the past, largely due to the lack of appropriate screening models, but rec

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Updates in the Clinical Development of Epacadostat and Other Indoleamine 2,3-Dioxygenase 1 Inhibitors (IDO1) for Human Cancers

Recent application of immunotherapy in clinical oncology revolutionized our management of advanced human cancers.Check point inhibitors targeting CTLA4 and PD-1/PD-L1 axis are immunotherapeutic agents currently available to treat a variety of cancers.However, a novel therapeutic approach is needed to further improve patient outcome with these agent

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